Clinical impact of fat clearing technique in nodal staging of rectal cancer after preoperative chemoradiotherapy.
10.4174/jkss.2013.85.1.30
- Author:
Im Kyung KIM
1
;
Beom Jin LIM
;
Jeonghyun KANG
;
Seong Ah KIM
;
Dongwon KANG
;
Seung Kook SOHN
;
Kang Young LEE
Author Information
1. Department of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. kylee117@yuhs.ac
- Publication Type:Original Article
- Keywords:
Fat clearing technique;
Preoperative chemoradiotherapy;
Rectal neoplasms
- MeSH:
Chemoradiotherapy;
Humans;
Lymph Nodes;
Rectal Neoplasms
- From:Journal of the Korean Surgical Society
2013;85(1):30-34
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: This study was designed to evaluate the efficacy of a fat clearing technique for accurate nodal staging of rectal cancer patients after preoperative chemoradiotherapy (CRT). METHODS: A total of 19 patients with rectal cancer within 10 cm from anal verge were divided into two groups: non-CRT group (n = 10) and CRT group (n = 9). For pathologic assessment, lymph node (LN) harvest was performed using conventional manual dissection followed by a fat clearing technique. RESULTS: A median of 3.0 additional LNs in non-CRT group and 3.8 LNs in CRT group were identified by the fat clearing technique. When subanalysis was performed in patients with fewer than 12 retrieved LNs, a median of 4.0 extra LNs in non-CRT group and 3.5 extra LNs in CRT group were identified after the fat clearing technique. None of additionally identified nodes were metastatic. In both groups, the median size of retrieved LNs following the fat clearing technique was smaller than that obtained by manual dissection (2.0 mm vs. 3.0 mm, P < 0.001). CONCLUSION: The fat clearing technique allowed detection of additional LNs that were missed by the manual method, but these detected LNs were not proven to be metastatic.
