A Case of Hemorrhagic Fever with Renal Syndrome by Seoul Virus Confirmed by Reverse Transcription-Polymerase Chain Reaction-Restriction Fragment Length Polymorphism.
- Author:
Sue SHIN
1
;
Jong Hyun YOON
;
Eui Chong KIM
Author Information
1. Department of Laboratory Medicine, Boramae Hospital1, Korea.
- Publication Type:Case Report
- Keywords:
Hemorrhagic fever with renal syndrome;
Seoul virus;
PCR-RFLP
- MeSH:
Adult;
Diagnosis;
Diarrhea;
Discrimination (Psychology);
Edema;
Female;
Fever;
Hantaan virus;
Hantavirus;
Hemorrhagic Fever with Renal Syndrome*;
Humans;
Korea;
Myalgia;
Seoul virus*
- From:The Korean Journal of Laboratory Medicine
2005;25(4):262-266
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Members of the genus Hantavirus are the etiologic agents of hemorrhagic fever with renal syndrome (HFRS), the diagnosis of which is somewhat difficult because several diseases share similar early clinical presentations such as fever and petechia. In Korea, Hantaan virus and Seoul virus are the causative organisms of HFRS, and the infection caused by Seoul virus is milder than that caused by Hantaan virus. We report a 44-year-old woman, who visited our hospital due to general weakness, fever, myalgia, facial edema and diarrhea. She was diagnosed with HFRS caused by Seoul virus. The antibody against Hantaan virus was positive by an indirect immunofluorescent test and the discrimination between Hantaan and Seoul viruses was done by RT-PCR-RFLP (reverse transcriptionpolymerase chain reaction-restriction fragment length polymorphism) against viral S segment.
