The Role of Radiotherapy for the Treatment of Gastric MALT Lymphoma.
- Author:
Jae Sook AHN
1
;
Taek Keun NAM
Author Information
1. Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea. f0115@chonnam.ac.kr
- Publication Type:Review
- Keywords:
Gastric MALToma;
Radiotherapy;
Extanodal marginal zone lymphoma
- MeSH:
Asian Continental Ancestry Group;
Consensus;
Disease-Free Survival;
Helicobacter pylori;
Humans;
Incidence;
Lymphoid Tissue;
Lymphoma;
Lymphoma, B-Cell, Marginal Zone
- From:Korean Journal of Medicine
2012;83(6):712-717
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Gastric mucosa-associated lymphoid tissue (MALT) lymphoma represents approximately 9% of all malignant lymphoma in Korean, and its incidence is higher than that of western and other Asian countries. Helicobacter pylori eradication is the first line treatment in limited stage gastric MALT lymphoma. There is no consensus about initial treatment with chemotherapy or radiotherapy for the patient with insufficient response to H. pylori eradication or H. pylori negative. Radiotherapy is a conventional therapeutic modality and showed the excellent long term results. The radiotherapy for limited gastric MALT lymphoma shows that the 4-5-year disease free survival rate is 85-100% and acute toxicities is reasonable. However, only non-randomized studies support a role of local radiotherapy in gastric MALT lymphoma.
