Effects of dietary acetaminophen and vitamin C supplement on serum cortisol and tumor necrosis factor-alpha concentrations in pigs vaccinated with foot-and-mouth disease vaccine.
10.14405/kjvr.2017.57.3.197
- Author:
Chun Nam CHA
1
;
Beom Jun LEE
;
Eun Kee PARK
;
Chang Yeol YOO
;
Suk KIM
;
Hu Jang LEE
Author Information
1. Engineering Research Institute and Department of Industrial Systems Engineering, Gyeongsang National University, Jinju 52828, Korea.
- Publication Type:Brief Communication
- Keywords:
acetaminophen;
cortisol;
foot-and-mouse disease vaccination;
pigs;
tumor necrosis factor-alpha
- MeSH:
Acetaminophen*;
Animals;
Ascorbic Acid*;
Foot-and-Mouth Disease*;
Hydrocortisone*;
Necrosis;
Swine*;
Tumor Necrosis Factor-alpha*;
Vitamins*
- From:Korean Journal of Veterinary Research
2017;57(3):197-200
- CountryRepublic of Korea
- Language:English
-
Abstract:
This study evaluated the effect of a combination of acetaminophen and vitamin C (CAV) on reducing serum cortisol and tumor necrosis factor-α (TNF-α) concentrations in piglets vaccinated with foot-and-mouth disease (FMD) vaccine. Piglets were vaccinated with FMD vaccine and treated with CAV at concentrations of 0.0, 0.5, 1.0, and 2.0 kg/ton feed (P-CON, AD-1, AD-2, and AD-3, groups, respectively) for 5 days post-vaccination. Cortisol and TNF-α levels at 5 days post-treatment in the AD-1–3 groups were significantly lower than that in the P-CON group (p < 0.05). There were no significant differences between AD-2 and AD-3 groups and non-vaccinated, non-CAV-treated piglets.
