A Case Report of Invasive Infection due to Trichosporon beigelii in a Patient with Acute Leukemia.
- Author:
Hyun LIM
1
;
Dal Sik KIM
;
Hye Soo LEE
;
Sam Im CHOI
Author Information
1. Department of Laboratory Medicine, Chonbuk National University Medical School, Korea. leehs@moak.chonbuk.ac.kr
- Publication Type:Case Report
- Keywords:
Trichosporon beigelii;
Acute leukemia;
Imunocompromised
- MeSH:
Adult;
Amphotericin B;
Anti-Bacterial Agents;
Drug Therapy;
Fever;
Humans;
Immunocompromised Host;
Leukemia*;
Leukemia, Myeloid, Acute;
Male;
Neutropenia;
Shock, Septic;
Trichosporon*;
Trichosporonosis
- From:Korean Journal of Clinical Microbiology
2002;5(2):151-154
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic infection due to Trichosporon beigelii is uncommon but increasingly reported in immunocompromised patients. Trichosporonosis is often refractory to conventional antifungal therapy and frequently fatal. We report a case of systemic T. beigelii infection in a patient with acute leukemia. The 35-year-old male patient had been diagnosed as acute myelogenous leukemia with severe neutropenia and received cytotoxic drug therapy. As a fever developed on the day 21 of chemotherapy, broad spectrum antibiotics were administered empirically. Even though an antifungal drug, amphotericin B was replaced because the blood cultures resulted in T. beigelii, the patient died of the septic shock. We think that T. beigelii should be included as a potential life-threatening pathogen capable of causing widespread systemic disease in the immunocompromised host.
