A Clinical and Pathological Observation of Microinvasive Carcinoma of Cervix.
- Author:
Myung Joo KIM
;
Hyun Chan KIM
- Publication Type:Original Article
- MeSH:
Biopsy;
Busan;
Cervix Uteri*;
Conization;
Diagnosis;
Female;
Gynecology;
Hemorrhage;
Humans;
Obstetrics;
Prognosis;
Retrospective Studies;
Uterine Cervical Neoplasms
- From:Korean Journal of Gynecologic Oncology and Colposcopy
1993;4(4):20-31
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The transition from preinvasive to invasive disease is a crucial juncture in the development of cervical cancer. The clinical experience that microvasive lesions carry a better prognosis justifies a sepetate diagnostic category. Besides clinical and cliagmostic problerns, the rnicroinvasive cervical cancer presents morphological peculiarities. To investigate the clinieal and pethological aspects of micrenvasive eervical carcinornn, a retrospective study was made on 40 cases, histologically reconfirrned surgical specimens, which had been treated during the period from March, 198I3 to March, 1992 at, Departrnent of Obstetrics and Gynecology, Pusan Paik Hospital, Inje University. The results obtained were as follows ; 1. Mean age of 40 patents was 44.6 year old, all were rnultipatous. Nineteen cases helonged to I s, and 21 cases to I a2. 2. Main presenting symptoms were leukorr hea and/or genital bleeding and the majority of patients showed cervical erosion on groas finding, 3. The corresponding rate of Pap, smear to histologic diagnosis was approximately 67.5%, However, corresponding rate within one histologie grade was about 85%. 4, Aecording to the eolpuacapie examination, less than half of the examined cases revealed suspected abnormal findings suggeeting invasive lesion. 5. As to the reports of punch biopsy, 64.8% of cases showed microinvasive and/or inuasive lesian. With additional diagnostic conization of cervix, the preoperative diagnosis were correct in 82.5%. 6. Histopathological reevaluatin ef surgiral specimens revealed positive correlation between depth of stromal invasion and width of leaior, confluent growth pattern, numher of invasive foci, and invasion of capillary-like spaee, respectively.
