Gastric Adenocarcinoma in Patient with Pernicious Anemia: A Case Report.
10.5230/jkgca.2007.7.1.38
- Author:
Byung Soo KIM
1
;
Jong Won KIM
;
In Kyu LEE
;
Dong Chul KIM
;
Woo Ho KIM
;
Hyuk Joon LEE
;
Han Kwang YANG
Author Information
1. Department of Surgery, Seoul National University College of Medicine, Seoul, Korea. hkyang@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Pernicious anemia;
Atrophic gastritis;
Gastric cancer
- MeSH:
Adenocarcinoma*;
Adult;
Anemia;
Anemia, Pernicious*;
Biopsy;
Dizziness;
Female;
Gastrectomy;
Gastritis, Atrophic;
Gastroscopy;
Humans;
Lymph Node Excision;
Stomach;
Stomach Neoplasms
- From:Journal of the Korean Gastric Cancer Association
2007;7(1):38-41
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Increased risk of gastric cancer has been reported in patients with chronic atrophic gastritis that develops in conjunction with pernicious anemia. We report here a case of a gastric adenocarcinoma associated with pernicious anemia. A 40-year-old female patient had been diagnosed with anemia 6 years earlier at a local hospital. One month ago, she visited our hospital for aggravated dizziness and newly developed epigastric soreness. Her blood hemoglobin level was 4.2 g/dl, and a gastroscopic work-up for anemia discovered a 2.5-cm-sized, slightly elevated mucosal lesion at the anterior wall of the high body in the stomach. The biopsy of this lesion revealed a moderately-differentiated adenocarcinoma. She underwent a total gastrectomy with a Roux en Y esophagojejunostomy with D2 lymph node dissection. The final stage of the gastric carcinoma was identified as T1N0M0. Based on this experience, we recommend that a follow-up gastroscopy be performed in patients with pernicious anemia with atrophic gastritis because of the increased risk of gastric cancer in patients with pernicious anemia.