Immunoglobulin G4-Related Inflammatory Pseudotumor Presenting as a Solitary Mass in the Stomach.

Author: Hong Ryeol CHEONG ¹ ; Bong Eun LEE ; Geun Am SONG ; Gwang Ha KIM ; Sung Gyu AN ; Won LIM
Author Information

1. Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea. bongsul@hanmail.net
Publication Type:Case Report
Keywords: Immunoglobulin G4-related sclerosing disease; Pseudotumor; Stomach
MeSH: Fibrosis; Granuloma, Plasma Cell*; Immunoglobulins*; Lymphocytes; Plasma Cells; Stomach*; Unnecessary Procedures
From:Clinical Endoscopy 2016;49(2):197-201
CountryRepublic of Korea
Language:English
Abstract: Immunoglobulin G4 (IgG4)-related disease (IgG4RD) is a relatively recently recognized entity that is histopathologically characterized by an extensive infiltration of lymphocytes and IgG4-positive plasma cells with dense fibrosis. IgG4RD is now known to affect any organ system, and a few cases of gastrointestinal lesions have also been reported. However, solitary IgG4RD of the stomach is still very rare. Furthermore, as it can mimic malignant conditions, it is important to recognize this disease to avoid unnecessary surgery. Herein, we present a case of IgG4RD presenting as an isolated subepithelial mass in the stomach.