Clinical Characteristics of Gastrointestinal Carcinoid Tumors.
- Author:
Myoung Hee LEE
1
;
Sung Jae SHIN
;
Su Jin JEON
;
Sun Gyo LIM
;
Yoon Chul LEE
;
Jae Chul HWANG
;
Kee Myung LEE
;
Kwang Jae LEE
;
Jin Hong KIM
Author Information
1. Department of Gastroenterology, Ajou University School of Medicine, Suwon, Korea. Shsj9128@ajou.ac.kr
- Publication Type:Original Article
- Keywords:
Carcinoid tumor;
Metastasis;
Predictive factor
- MeSH:
Appendix;
Carcinoid Tumor;
Colon;
Duodenum;
Humans;
Multivariate Analysis;
Muscles;
Neoplasm Metastasis;
Prognosis;
Rectum;
Retrospective Studies;
Stomach;
Ulcer
- From:Korean Journal of Gastrointestinal Endoscopy
2010;40(6):347-351
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND/AIMS: Various factors have been reported that can predict the clinical course and outcome of patients with gastrointestinal (GI) carcinoid tumors. We analyzed the clinical characteristics of GI carcinoid tumors and the factors associated with metastasis. METHODS: We retrospectively analyzed the clinical manifestations, treatment modalities and prognosis of 83 patients with GI carcinoid tumors. RESULTS: The mean age of the patients was 48 years old. The locations of the carcinoid tumors were rectum (n=60), stomach (n=12), duodenum (n=6), appendix (n=4) and colon (n=1). The most common symptom was non-specific (n=65, 79.5%), and the mean tumor size was 11.2 mm. The main treatment modality was endoscopic resection (n=66, 79.5%). Nine patients showed metastasis, and all of their tumors were larger than 2 cm. Univariate analysis revealed that size, ulceration and invasion of the proper muscle layer were significant factors associated with metastasis. Tumor size (p=0.001) was the only independent factor on multivariate analysis. CONCLUSIONS: The diagnosis of small sized, asymptomatic GI carcinoid tumors has increased and endoscopic treatment was a useful modality. Tumor size was a predictive factor for metastasis.
