A case of nephrocalcinosis with primary aldosteronism.
- Author:
Byung Chul SHIN
1
;
Bum Yun KIM
;
Bong Kwan RYU
;
Hyun Lee KIM
;
Jong Hoon CHUNG
Author Information
1. Department of Internal Medicine, College of Medicine, Chosun University, Kwangju, Korea. jhchung@mail.chosun.ac.kr
- Publication Type:Case Report
- Keywords:
Primary aldosteronism;
Hypokalemia;
Nephrocalcinosis
- MeSH:
Abdomen;
Abdominal Pain;
Adrenocorticotropic Hormone;
Adult;
Aldosterone;
Blood Pressure;
Calcium;
Creatinine;
Humans;
Hyperaldosteronism*;
Hypertension;
Hypokalemia;
Magnesium;
Male;
Nephrocalcinosis*;
Plasma;
Potassium;
Renin;
Sodium;
Urine Specimen Collection
- From:Korean Journal of Medicine
2003;65(1):111-114
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Primary aldosteronism is defined as hypertension, hypokalemia, increased serum aldosteron, decreased serum renin activity. It has been known that prolonged hypokalemia, renal cyst formation and impairment of renal function. However, nephrocalcinosis associated with primary aldosteronism is rarely reported. A 31-year-old male was admitted to our hospital because of abdominal pain and uncontrolled hypertention which developed 2 years earlier. At admission, blood pressure 180/100 mmHg. Biochemical findings indicated sodium 146 mEq/L, potassium 2.3 mEq/L, BUN 8.2 mg/dL, creatinine 1.1 mg/dL, calcium 10.7 mg/dL, phosphate 5.7 mg/dL, magnesium 1.8 mg/dL. Twenty-four hour urine collection indicated sodium 108 mEq, potassium 32 mEq, calcium 75 mg, phosphate 72 mg, magnesium 8.0 mg. The hormone study revealed PTH 22.7 pg/mL (normal: 9~55 pg/mL), ACTH 8 pg/mL (normal: 6~56.7 pg/mL), aldosterone 51.0 ng/dL (normal: 1~16 ng/dL), plasma renin activity below 0.01 ng/mL/hr (normal: 0.15~233 ng/mL/hr). Abdominal sonography showed homogenous increased medullary echoes and multiple calcification. The abdomen CT showed adrenal mass (1 x 1 cm) consistent with adrenal tumor. Adrenalrectomy was performed on the 16th hospital day and clinical symptoms, blood pressure and hypokalemia improved shortly after operation.
