Fertility preservation in patients with early epithelial ovarian cancer.
- Author:
Yong Soon KWON
1
;
Ho Suap HAHN
;
Tae Jin KIM
;
In Ho LEE
;
Kyung Taek LIM
;
Ki Heon LEE
;
Jae Uk SHIM
;
Jung Eun MOK
Author Information
- Publication Type:Original Article
- Keywords: Fertility preservation; Epithelial ovarian cancer; Staging operation
- MeSH: Chemotherapy, Adjuvant; Fertility; Fertility Preservation; Follow-Up Studies; Humans; Infant; Medical Records; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Retrospective Studies
- From:Journal of Gynecologic Oncology 2009;20(1):44-47
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: To assess the role of fertility preservation in the treatment of patients with early epithelial ovarian cancer (EOC). METHODS: We retrospectively analyzed the medical records of 21 patients with early EOC from January 1995 to December 2006. All eligible patients with a strong desire to preserve fertility were younger than 35 years and underwent fertility-sparing surgery with or without adjuvant chemotherapy. RESULTS: Twenty-one eligible patients with a median age of 26.7 years (range, 20 to 33 years) were identified, and the mean follow-up period was 43 months (range, 5 to 86 months). Only one patient with stage IC recurred 34 months after the first operation. A total of five patients were able to become pregnant at least once after the first fertility preserving treatment, with or without adjuvant chemotherapy. All five patients succeeded in full-term vaginal delivery with healthy infants. No patients died of their disease. CONCLUSION: Fertility preserving treatment in patients with early EOC can be considered as a proper treatment strategy in patients with early EOC, who have the strong desire for fertility preservation.
