Intravenous Recombinant Tissue Plasminogen Activator Thrombolysis in a Patient with Acute Ischemic Stroke Secondary to Aortic Dissection.
- Author:
Keun Sik HONG
1
;
So Young PARK
;
Seon Il WHANG
;
So Young SEO
;
Dong Ha LEE
;
Han Joon KIM
;
Joong Yang CHO
;
Yong Jin CHO
;
Woo Ik JANG
;
Chang Young KIM
Author Information
- Publication Type:Case Report
- Keywords: aortic dissection; ischemic stroke; thrombolysis; recombinant tissue plasminogen activator
- MeSH: Abdominal Pain; Emergencies; Female; Humans; Infarction, Middle Cerebral Artery; Middle Aged; Physical Examination; Stroke; Thorax; Tissue Plasminogen Activator
- From:Journal of Clinical Neurology 2009;5(1):49-52
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND: Acute ischemic stroke secondary to aortic dissection (AoD) is challenging in the era of thrombolysis owing to the diagnostic difficulty within a narrow time window and the high risk of complications. CASE REPORT: A 64-year-old woman with middle cerebral artery occlusion syndrome admitted to the emergency room within intravenous recombinant tissue plasminogen activator (rt-PA) time window. Her neurological symptoms improved during thrombolysis, but chest and abdominal pain developed. Repeated history-taking, physical examination, and imaging studies led to the timely diagnosis and surgical treatment of AoD, which produced a successful outcome. CONCLUSIONS: Clinical suspicion is invaluable for the diagnosis of this rare cause of stroke. Considering the stroke mechanism and complications, the risks of thrombolysis might outweigh its benefits.
