Effects of different sizes of Hydroxyapatite/beta-Tricalcium phosphate particles on vertical bone augmentation.
10.4047/jkap.2010.48.4.259
- Author:
Jung Bo HUH
1
;
Dong Hee JUNG
;
Ji Sun KIM
;
Sang Wan SHIN
Author Information
1. Advanced Prosthodontics, Graduate School of Clinical Dentistry, Korea University / Institute for Clinical Dental Research, Seoul, Korea. swshin@korea.ac.kr
- Publication Type:Original Article
- Keywords:
beta-TCP/HA;
Titanium mesh;
Particle size;
Vertical augmentation
- MeSH:
Humans;
Mandrillus;
Osteogenesis;
Particle Size;
Rabbits;
Skull;
Titanium;
Transplants
- From:The Journal of Korean Academy of Prosthodontics
2010;48(4):259-265
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study was aimed to evaluate the effect of different sizes of beta-TCP/HA particles on vertical bone augmentation using titanium mesh in the cranium of rabbits. MATERIAL AND METHODS: Six white rabbits weighing 5kg were used. Four circular grooves of 6mm diameter were made by trephine, and five small holes were drilled in the inner surface of each circular gooves. Different sizes of grafts (small 0.3 - 0.5 mm, medium 0.5 - 1.0, large 1.0 - 2.0 mm) were placed respectively in the experimental groups. Titanium mesh (height 3 mm, width 6 mm) was placed. After 8weeks healing period, the rabbits were euthanized, and the specimens were prepared for histological findings. New bone formation and remaining graft area were measured to calculate the ratio of areas occupying the inner space of titanium mesh. Mann-Whitney U-test and Wilcoxon signed rank-test were used for statistical analysis (alpha = .05). RESULTS: The experimental groups with beta-TCP/HA graft showed a significantly higher new bone formation (P = .003). Comparing different sizes of beta-TCP/HA, there was no statistical difference in terms of new bone formation. The vertical bone formation (i.e. new bone and graft area) was significantly greater in beta-TCP/HA groups (P = .001). In comparison between different sizes of beta-TCP/HA, medium size group had significantly greater area than large particle size group (P = .039). CONCLUSION: The use of beta-TCP/HA with titanium mesh showed a higher vertical bone formation, particularly the medium sized beta-TCP/HA particles (0.5 - 1.0 mm) produced better results in vertical bone augmentation.
