A Case of Extrapontine Myelinolysis Without Central Pontine Myelinolysis Following Hyponatremia.
- Author:
Kyung Won CHO
1
;
Jung Gyun NA
;
Won Young JUNG
;
Ki Hyun CHO
;
Sei Jong KIM
Author Information
1. Department of Neurology, College of Medicine, Chosun Universtiy.
- Publication Type:Original Article
- MeSH:
Alcoholism;
Brain;
Caudate Nucleus;
Consciousness;
Demyelinating Diseases;
Hepatitis;
Humans;
Hyponatremia*;
Magnetic Resonance Imaging;
Middle Aged;
Myelinolysis, Central Pontine*;
Pons;
Pseudobulbar Palsy;
Putamen;
Quadriplegia
- From:Journal of the Korean Neurological Association
1992;10(3):375-381
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Central pontine myelinolysis (CPM) is characterized by regions of demyelination throughout the brain but most prominent in the pons. The symptoms of CPM include rapidly evolving quadriplegia, pseudobulbar palsy and varying degree of altered consciousness. The exact pathogenesis is unknown. We report a rare case of extrapontine myelinolysis (EPM) without CPM; A 49-year-old man with chronic alcoholism and chronic type B hepatitis were presented with clinical symptoms of rapidly progressive quadriplegia and pseudobulbar palsy preeded by hyponatremia. Magnetic resonance imaging in this patient showed bilateral increased T2-weighted signals in the caudate nucleus and the putamen.
