A Case of Multiple Mononeuropathy Associated with Polyarteritis Nodosa.
- Author:
Sung Hoon LEE
1
;
Soon Ki RHO
;
Chang Won SONG
;
Sang Ik LEE
;
Kyu Hyun PARK
;
Sang Wook KIM
Author Information
1. Department of Neurology, College of Medicine, Pusan National University.
- Publication Type:Original Article
- MeSH:
Antigen-Antibody Complex;
Arteries;
Biopsy;
Mononeuropathies*;
Polyarteritis Nodosa*;
Polyneuropathies;
Sural Nerve
- From:Journal of the Korean Neurological Association
1992;10(3):395-400
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Polyarteritis nodosa(PAN) has been depicted as a necrotizing arteritis of small and medium-sized muscular arteries, affecting multiple organ systems throughout the body. The etiology of PAN remains unknown, but the histopathologic resemblance to chronic serim sickness has suggested an immune complex pathogenesis. The peripheral nervous system(PNS) is more frequently affected (in about 20-50% of patients) than the central nervous system(in about 10-20% of patients). Although multiple mononeuritis multiplex is generally considered to be the typical PNS manifestation of PAN, distal symmetrical polyneuropathy may occur more frequently than previous recognized. We report a case of polyarteritis nodosa with mononeuritis multiplex and distal symmetrical polyneuropathy, which was diagnosed by electrophysiological study and biopsies of muscle and sural nerve.
