The Distribution of I/D Polymorphism in the ACE Gene between Korean Young Controls and Athletes.
10.11637/kjpa.2005.18.4.263
- Author:
Jae Koo LEE
1
;
Doo Jin PAIK
;
Byung Yong KANG
;
Min Hee JANG
;
Kang Oh LEE
Author Information
1. Department of Leisure and Sports, Sahmyook University.
- Publication Type:Original Article
- Keywords:
ACE;
Athletes;
Korean
- MeSH:
Alleles;
Athletes*;
Athletic Performance;
Genotype;
Humans;
Sports
- From:Korean Journal of Physical Anthropology
2005;18(4):263-270
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A number of genetic and environmental factors influence athletic performance. Cardiovascular fitness is an important factor of athletic success, and ACE gene is a good candidate for regulating cardiac and vascular function. Because younger subjects have less chance of being exposed to environmental factors than older ones, genetic factors have a relatively greater influence on younger subjects. The aim of this study was to investigate the distribution of I/D polymorphism in the ACE gene between Korean young controls and athletes. By association study, there were no significant differences in genotype and allele distributions between two groups, respectively (P> 0.05). When stratified by sporting disciplines, the significant difference in distribution was not also detected in our study (P> 0.05). These results do not support the hypothesis that the I/D polymorphism in the ACE gene is associated with endurance performance in Korean young subjects.
