A Case of Anti-LKM 1 Positive Autoimmune Hepatitis Accompanied by Systemic Lupus Erythematosus.
- Author:
Dae Han CHOI
1
;
Hae Kyung KIM
;
Tae Il PARK
;
Byung Min JOHN
;
Sung Hwan KANG
;
Yoon Serk LEE
;
Tae Hyun KIM
;
Uh Joo LEE
;
Tae Seung LEE
;
Gwi Ok YOON
Author Information
1. Department of Internal Medicine, Kwang Myung SungAe Hospital, Gwangmyeong, Korea. kimhkgi@naver.com
- Publication Type:Case Report ; English Abstract
- Keywords:
Autoimmune hepatitis;
Systemic lupus erythematosus
- MeSH:
Antibodies, Antinuclear/analysis;
Autoantibodies/*analysis;
Echocardiography;
Female;
Hepatitis, Autoimmune/complications/*diagnosis/immunology;
Humans;
Liver/pathology;
Lupus Erythematosus, Systemic/complications/*diagnosis/immunology;
Young Adult
- From:The Korean Journal of Gastroenterology
2008;51(3):190-193
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Overlap of autoimmune hepatitis and systemic lupus erythematosus (SLE) is a comparatively rare condition. Although both autoimmune hepatitis and SLE can share common autoimmune features such as polyarthralgia, hypergammaglobulinemia and positive ANA, it has been considered as two different entities. We report a case of anti-LKM1 positive autoimmune hepatitis who developed SLE two years later. The presence of interface hepatitis with lymphoplasma cell infiltrates and rosette formation points to the autoimmune hepatitis rather than SLE hepatitis. Autoimmune hepatitis is infrequently accompanied by SLE, therefore, it could be recommended to investigate for SLE in patients with autoimmune hepatitis.
