Characteristics and Detection Rate of Thyroidal Incidentaloma using ¹⁸F-FDG PET-CT.
10.16956/kjes.2008.8.1.38
- Author:
Kang Young RHEE
1
;
Gun KOH
;
Sun Kuk KIM
;
Jin Chul KOH
;
Haeng Soo KIM
;
Sang Yong CHOI
;
Shin Hee PARK
;
Yong Whi PARK
Author Information
1. Department of Surgery, Gwangmyeong Sungae General Hospital, Gwangmyeong, Korea. sungaegs@sungae.co.kr
- Publication Type:Original Article
- Keywords:
Thyroid;
Thyroid cancer;
¹⁸F-FDG PET-CT;
SUV;
Incidentaloma
- MeSH:
Biopsy, Fine-Needle;
Fluorodeoxyglucose F18;
Healthy Volunteers;
Humans;
Pathology;
Prevalence;
Retrospective Studies;
Thyroid Gland*;
Thyroid Neoplasms;
Ultrasonography
- From:Korean Journal of Endocrine Surgery
2008;8(1):38-42
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: PET-CT is often used to differentiate benign or malignant thyroid incidentalomas. In this retrospective study, we evaluated whether the ¹⁸F-FDG uptake pattern and PET-CT findings improved accuracy over the standardized uptake value (SUV). METHODS: ¹⁸F-FDG PET-CT was performed on 2,178 subjects from August, 2004, to October, 2007, in Sung-ae Hospital. PET-CT was performed on 806 patients (37%) with suspected or known nonthyroidal cancer and 1,372 healthy subjects (63%) without a previous history of cancer. We investigated the clinical characteristics of patients, history, standardized uptake value (SUV), ultrasonography, and hormone levels in blood. Thyroidal cancer was confirmed by ultrasonography-guided fine needle aspiration and pathology after thyroid operation. RESULTS: The prevalence of focal thyroid lesions on PET-CT was 8.8% (191/2178). Thyroid cancer confirmation was 7.9% (15/191). The maximum SUV of malignant thyroid lesions were significantly higher than that of benign lesions (7.00±3.08 vs. 4.49±1.84, P<0.001). CONCLUSION: PET-CT image interpretation that includes 18F-FDG uptake and SUV is better than PET-CT alone for differentiating benign and malignant lesions. Thyroid cancer risk increases as SUVmax levels increase.
