Treatment of Late Bleb Leak with Human Amniotic Membrane Transplantation.
- Author:
Seonghee KIM
1
;
Sang Il CHOI
;
Changwon KEE
Author Information
1. Department of Ophthalmology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Late bleb leak;
Amniotic membrane transplantation;
MMC;
Trabeculectomy
- MeSH:
Amnion*;
Antimetabolites;
Basement Membrane;
Blister*;
Graft Rejection;
Humans*;
Membranes;
Trabeculectomy
- From:Journal of the Korean Ophthalmological Society
2000;41(4):1023-1027
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Late bleb leak after trabeculectomy is a serious and intractable complication and its frequency is increasing as antimetabolites are used in the surgery. Various modalities have been challenged in the treatment of late bleb leak but the results have not been satisfactory.Amniotic membrane is avascular tissue with thick basement membrane and rich stroma, and it can modulate wound.As it does not express HLA, it doesn t induce graft rejection. With the use of these characteristics of amniotic membrane, we report a case in which late bleb leak after trabeculectomy with MMC was successfully treated with amniotic membrane transplantation maintaining bleb function.
