Metabolic Changes after Revascularization in a Patient with Innominate Artery Occlusion by Localized in vivo Proton Magnetic Resonance Spectroscopy.
10.3346/jkms.2003.18.2.267
- Author:
Yong Pil CHO
1
;
Jung Hee LEE
;
Geun Eun KIM
Author Information
1. Department of Surgery, University of Ulsan College of Medicine, Gangneung Asan Hospital, Gangneung, Korea. ypcho@knh.co.kr
- Publication Type:Case Report
- Keywords:
Magnetic Resonance Spectroscopy;
Brachiocephalic trunk;
Arterial Occlusive Diseases;
Reperfusion
- MeSH:
Arterial Occlusive Diseases/pathology;
Brachiocephalic Trunk/pathology*;
Brachiocephalic Trunk/surgery;
Brain/metabolism*;
Cerebral Revascularization*;
Human;
Magnetic Resonance Imaging;
Male;
Middle Aged;
Protons
- From:Journal of Korean Medical Science
2003;18(2):267-271
- CountryRepublic of Korea
- Language:English
-
Abstract:
Localized in vivo proton magnetic resonance spectroscopy (1H-MRS) has been used to measure the metabolic status of the human brain in a non-invasive manner; thus, it is often called "a non-invasive biochemical assay". MRS is more sensitive than magnetic resonance imaging (MRI) in detecting ischemic damage by measuring the metabolic changes that occur prior to the anatomic changes. We report a patient who presented with innominate artery occlusion and symptoms of posterior circulation insufficiency and showed favorable metabolic changes by 1H-MRS after revascularization. He showed no visible lesion in brain MRI, but in 1H-MRS, decreased N-acetylaspartate (NAA) signal was noted in a resting state. After revascularization, both symptomatic improvement and recovery of NAA signal were observed. 1H-MRS may provide valuable clinical information in diagnosis and management of cerebral hypoperfusion at a much earlier stage prior to the anatomic changes.
