A Clinical Study on Pseudomembranous Colitis.
- Author:
Pan Sik LIM
;
Han Doo YUN
;
Kyong Wook YIM
;
In Sung SONG
;
Kyoo Wan CHOI
;
Chung Yong KIM
- Publication Type:Original Article
- MeSH:
Abscess;
Biopsy;
Cataract;
Cervix Uteri;
Cholestyramine Resin;
Colitis;
Colon, Descending;
Colon, Sigmoid;
Enterocolitis, Pseudomembranous*;
Female;
Humans;
Korea;
Metronidazole;
Nasal Polyps;
Osteoarthritis;
Rectum;
Seoul;
Sex Distribution;
Sigmoidoscopy;
Trimethoprim-Sulfamethoxazole Combination;
Trimethoprim, Sulfamethoxazole Drug Combination
- From:Korean Journal of Gastrointestinal Endoscopy
1987;7(1):13-17
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The purpose of this study is to review the clinical and pathological features of pseudomembranous colitis in Korea. Ten cases of psedomembranous colitis, which were diagnosed by sigmoidoscopy and biopsy at the Seoul National University Hospital from May 1982 to occtober 1985, were analyzed in terms of the age and sex distribution, underlying diseases, presumptive causative antimicrobials, symptomatology, involved site and tratment. 1) The disease was more prevalent above sixth decade with a slight preponderance on the female. 2) The underlying diseases of the patients were the uterine cervix cancer in 3 cases and one case each of the nasal polyp, cataract, degenerative arthritis, tuberculous gradmuloma, SLE with menngitis, CVA and gingival abscess. 3) As for the presumptive causative drugs, cephalosporin were assaciated in 6 cases, aminoglycoside m 7 cases, penlcillin in 3 cases, Bactrim in 3 cases, antituberculosis drugs in 1 case and anticancer drugs in 1 case. 4) As for the anatotmical distribution of the lesion, the rectum was involved in 5 cases, the rectum and sigmoid colon in 4 cases and up to the descending colon in 1 case. 5) All the cases were cured by medical treatment. In 5 cases, discontinuation of the antimicrobial drugs and supportive care only were effective and in other 5 cases, vancamycin and/or metronidazole together vrith cholestyramine were added to the regimen.
