Efficacy of early steroid use in Mycoplasma pneumoniae pneumonia.
10.4168/aard.2017.5.5.280
- Author:
Hee Seong KIM
1
;
Myung Gon SONG
;
Yong Wook KIM
;
Kyoung Sim KIM
;
Eun Young KIM
;
Young KIM
;
Hae In JANG
;
Hyung Min CHO
Author Information
1. Department of Pediatrics, Kwangju Christian Hospital, Gwangju, Korea. drcho92@hanmail.net
- Publication Type:Original Article
- Keywords:
Mycoplasma pneumonia;
Steroid;
Macrolide
- MeSH:
Fever;
Gwangju;
Hospitalization;
Humans;
Macrolides;
Mycoplasma pneumoniae*;
Mycoplasma*;
Pneumonia*;
Pneumonia, Mycoplasma*;
Prospective Studies;
Radiography, Thoracic;
Steroids
- From:Allergy, Asthma & Respiratory Disease
2017;5(5):280-286
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aim of this study was to evaluate whether or not the early use of steroid is useful for treating Mycoplasma pneumoniae pneumonia. METHODS: A prospective study was conducted on 85 patients with M. pneumoniae pneumonia admitted to Gwangju Christian Hospital between September 2015 and April 2016. A total of 85 patients were enrolled. Of these, 33 were treated with steroids (methyl-prednisolone 1 mg/kg/day), while 52 were not; both were treated with macrolides. The overall duration of fever was compared between the 2 groups and findings on chest radiographs were evaluated for their deterioration. RESULTS: The duration of fever after admission (1.36±0.92 days vs. 2.17±1.30 days, P=0.003) and the overall duration of fever (4.42±2.13 days vs. 6.07±2.59 days, P=0.003) were significantly lower in the steroid group. The duration of fever before admission was not different between the steroid and macrolide groups (3.06±1.74 days vs. 3.90±2.21 days, P=0.068). On chest radiographs taken 3 days later, 1 of 33 patients in the steroid group and 5 of 50 patients in the macrolide group worsened, although there was no statistically significant difference between the 2 groups (P=0.395). There was no significant difference in the duration of hospitalization between the 2 groups (6.72±1.54 days vs. 6.92±1.87 days, P=0.618). CONCLUSION: Early administration of steroids on patients with M. pneumoniae pneumonia reduced the duration of fever, but there was no difference in duration of admission and x-ray deterioration.
