The Efficacy of Sentinel Node Biopsy Using Subareolar Injection of Radioactive Material in Breast Cancer.
10.4048/jkbcs.2003.6.3.180
- Author:
Hyun Ah KIM
1
;
Jae Hyuk LEE
;
Byung In MOON
;
Kum Ja CHOI
;
Soon Hee SUNG
;
Hye Young CHOI
;
Hyun Suk SUH
Author Information
1. Department of Surgery, College of Medicine, Ewha Womans University, Seoul, Korea. mbit@ewha.ac.kr
- Publication Type:Original Article
- Keywords:
Sentinel node;
Subareolar injection;
Lymphoscintigraphy
- MeSH:
Biopsy*;
Breast Neoplasms*;
Breast*;
Colloids;
Female;
Humans;
Lymph Nodes;
Lymphoscintigraphy;
Neoplasm Metastasis;
Prospective Studies;
Sulfur
- From:Journal of Korean Breast Cancer Society
2003;6(3):180-185
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study was designed to evaluate the feasibility of sentinel node biopsy (SNB) using subareolar injection of radioactive material in breast cancer. METHODS: The prospective study was performed of 112 breast cancers (T1 or T2 stages) at Ewha Womans University Mok-Dong Hospital from February 2001 to June 2003. Patients underwent lymphoscintigraphy using 99mTc sulfur colloid. The feasibility of SNB was assessed through comparison with simultaneous axillary node dissection. RESULTS: All patients were women, and the median age was 46 years. Internal mammary sentinel lymph node was identified in 2 cases (1.8%). The first node was appeared on lymphoscintigraphy around at 10.7 minutes after subareolar injection. Sentinel nodes could be identified in 111 (99.1%) among 112 patients with a gamma probe. The mean number of harvested sentinel nodes were 3.3 and metastasis was noted 80 of 368 nodes (21.7%). False negative rate was 4.1%. CONCLUSION: SNB using subareolar injection of radioactive material could be a alternative method to replace axillary node dissection in T1 or T2 breast cancers, especially in case of clinical node negative patients.
