Characteristic Muscle Involvement on Magnetic Resonance Imaging in Central Core Disease.
- Author:
Jee Young KIM
1
;
Joong Goo KIM
;
Jae Young LEE
;
Ji Hoon KANG
;
Jay Chol CHOI
;
Jung Seok LEE
;
Sa Yoon KANG
Author Information
1. Department of Neurology, Jeju National University School of Medicine, Jeju, Korea. neurokang@jejunu.ac.kr
- Publication Type:Case Report
- Keywords:
Central core disease;
MRI;
Muscle
- MeSH:
Biopsy;
Magnetic Resonance Imaging;
Magnetic Resonance Spectroscopy;
Magnetics;
Magnets;
Muscles;
Muscular Diseases;
Myopathy, Central Core;
Quadriceps Muscle
- From:Journal of the Korean Neurological Association
2011;29(1):31-33
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Central core disease (CCD) is a rare congenital myopathy characterized by central cores on muscle biopsy. We present three familial cases of CCD. The muscle pathology manifested as a predominance of type 1 muscle fibers and highly oxidative fibers with central cores. Muscle MRI showed selective involvement of the sartorius, vastus lateralis, and adductor magnus muscles. We suggest that muscle MRI can be used as an additional tool in the diagnosis of CCD.
