High Prevalence of Psychotropics Overdose among Suicide Attempters in Korea.
10.9758/cpn.2015.13.3.302
- Author:
Jinyoung KIM
1
;
Minseob KIM
;
Yoo ra KIM
;
Kyoung Ho CHOI
;
Kyoung Uk LEE
Author Information
1. Department of Psychiatry, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. mindcure@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Attempted suicide;
Drug overdose;
Psychotropic drugs;
Hypnotics and sedatives
- MeSH:
Agrochemicals;
Alprazolam;
Analgesics;
Benzodiazepines;
Drug Overdose;
Female;
Household Products;
Humans;
Hypnotics and Sedatives;
Korea*;
Male;
Prevalence*;
Psychotropic Drugs;
Suicide*;
Suicide, Attempted
- From:Clinical Psychopharmacology and Neuroscience
2015;13(3):302-307
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: The availability of suicide methods affects the risk of suicide attempts. This study examined the patterns of substances ingested by suicide attempters (SAs) and the characteristics of SAs using psychotropic overdoses. METHODS: Data for 384 of the 462 eligible SAs who used self-poisoning were analyzed. Demographic variables, clinical characteristics, and factors related to the suicide attempts were examined. RESULTS: There were 256 (66.7%) females and 128 (33.3%) males. Roughly half the SAs ingested psychotropics (n=179, 46.6%). Agricultural chemicals (n=84, 21.9%) were the second most frequently ingested substances, followed by analgesics (n=62, 16.1%), household products (n=27, 7.0%), and other prescribed medications (n=23, 6.0%). Among psychotropics, the most frequently overdosed drugs were sedative-hypnotics, including hypnotics (n=104) and benzodiazepines (n=78). SAs favored Z-drugs and alprazolam. When compared with SAs with non-psychotropic overdoses, significantly more SAs with psychotropic overdoses were female (76% vs. 58.5%, p<0.001) and had a psychiatric history (59.8% vs. 29.8%, p<0.001). They had significantly more previous suicide attempts (0.52+/-1.02 vs. 0.32+/-0.80, p<0.05) and lower risk (7.96+/-1.49 vs. 8.44+/-1.99, p<0.01) and medical severity (3.06+/-0.81 vs. 3.37+/-0.93, p<0.005) scores. CONCLUSION: Psychotropic overdose, especially with sedative-hypnotics, was a major method in suicide attempts. It is important that psychiatric patients are carefully evaluated and monitored for suicidality when prescribing psychotropics.
