Clinical Trial on the Antianginal Effect of Trapidil.
10.4070/kcj.1988.18.2.251
- Author:
Joo Hyun SON
;
Jong Geol SHIM
;
Jeong Hyun KIM
;
Heun Kil LIM
;
Bang Hun LEE
;
Chung Kyun LEE
- Publication Type:Clinical Trial ; Original Article
- MeSH:
Constipation;
Dizziness;
Electrocardiography;
Humans;
Male;
Muscle Cramp;
Trapidil*
- From:Korean Circulation Journal
1988;18(2):251-255
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Antianginal effect of Trapidil was evaluated in 30 patients (18 male and 12 females) with angina rectoris. The results were follows : 1) Antianginal effect of the drug were good in 18 cases (60%) and fair in 8 cases (37%), and there was no effect in 4 cases(13%). 2) Improvement in ECG changes was observed in 29%. 3) There were no significant change in CBC, RUA, LFT, serum electrolyte and lipid study before and after medication. 4) The adverse effects of trapidil were constipation, gastric cramp and dizziness, respectively one case. But they were not required discontinuing the medicetion. On the basis of these results, Trapidol was evaluated to be promising antianginal drug.
