Clinical Experience of Malignant Transformation of Multiostotic Fronto-Orbital Fibrous Dysplasia.
- Author:
Han Kyeol KIM
1
;
Yeong Min SEO
Author Information
1. Department of Plastic and Reconstructive Surgery, Kosin University College of Medicine, Busan, Korea. youngminps@hanmail.net
- Publication Type:Case Report
- Keywords:
Fibrous dysplasia;
Malignant transformation;
Reconstruction
- MeSH:
Blindness;
Drug Therapy;
Fibrous Dysplasia, Polyostotic;
Humans;
Incidence;
Lung;
Male;
Middle Aged;
Neoplasm Metastasis;
Osteosarcoma;
Recurrence;
Titanium
- From:Journal of the Korean Cleft Palate-Craniofacial Association
2006;7(2):87-90
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The malignant transformation of fibrous dysplasia is a rare condition and the incidence is estimated at 0.4% for fibrous dysplasia and 4% for Albright's syndrome. And fronto-orbital fibrous dysplasia can have a devastating outcome with high rates of recurrence and blindness, especially following incomplete resection. So a radical and extensive approach to treatment is recommended. We report the case of a multiostotic fronto-orbital fibrous dysplasia in a 54-year-old male patient which had a malignant transformation to osteosarcoma. There had been a recurrence after partial removal and no effect by chemotherapy. Although we had have a favorable outcome in functional and aesthetic aspects without any evidences of recurrence by total removal and reconstruction with titanium mesh, the patient died with lung metastasis 4 and half years later after the first operation.
