Acquired myasthenia gravis in a domestic shorthair cat with cranial mediastinal mass.
10.14405/kjvr.2016.56.2.121
- Author:
Doo Won SONG
1
;
Min Hee KANG
;
Hee Myung PARK
Author Information
1. Department of Veterinary Internal Medicine, College of Veterinary Medicine, Konkuk University, Seoul 05029, Korea. parkhee@konkuk.ac.kr
- Publication Type:Case Report
- Keywords:
acetylcholine receptor antibody titer;
myasthenia gravis;
thymoma
- MeSH:
Acetylcholine;
Animals;
Anorexia;
Cats*;
Child;
Constipation;
Depression;
Diagnosis;
Fever;
Humans;
Korea;
Male;
Muscle Weakness;
Myasthenia Gravis*;
Neck;
Neurologic Examination;
Thymoma;
Voice
- From:Korean Journal of Veterinary Research
2016;56(2):121-123
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 7-year-old castrated male domestic short-hair cat presented with anorexia, constipation, depression, and voice alteration. Physical and neurological examinations revealed hyperthermia (40.5℃), ventroflexion of the neck, reduced responses to external stimuli, generalized muscle weakness, and exercise intolerance. Thoracic radiographs revealed the presence of a cranial mediastinal mass. The history, clinical signs, and other examination results were compatible with acquired myasthenia gravis (MG). Acetylcholine receptor (AChR) antibody titers were determined to confirm MG and the serum AChR antibody concentration was 1.24 nmol/L (reference interval, < 0.3 nmol/L). This is the first diagnosis of acquired MG in a cat in Korea.