The clinical efficacy of body mass index as a predictor of in vitro fertilization and embryo transfer outcomes.
- Author:
Sang Don KIM
1
;
Byung Chul JEE
;
Seung Yup KU
;
Chang Suk SUH
;
Young Min CHOI
;
Jung Gu KIM
;
Shin Yong MOON
;
Seok Hyun KIM
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Seoul National University, Seoul, Korea. seokhyun@plaza.snu.ac.kr
- Publication Type:In Vitro ; Original Article
- Keywords:
Body mass index (BMI);
In vitro fertilization and embryo transfer (IVF-ET);
Pregnancy;
Prediction
- MeSH:
Body Mass Index*;
Embryo Transfer*;
Embryonic Structures*;
Estradiol;
Female;
Fertilization in Vitro*;
Gonadotropin-Releasing Hormone;
Gonadotropins;
Humans;
Oocytes;
Pregnancy;
Pregnancy Rate;
Retrospective Studies
- From:Korean Journal of Obstetrics and Gynecology
2005;48(9):2157-2165
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: To evaluate the clinical efficacy of body mass index (BMI) as a predictor of in vitro fertilization and embryo transfer (IVF-ET) outcomes. METHODS: Two hundred twenty-three IVF-ET cycles in 164 patients under 37 years using GnRH agonist long protocol were included in this retrospective study. All of the selected cases were divided into two groups by BMI of 24 kg/m2 and these two groups were compared in regard to the outcomes of IVF-ET. RESULTS: There were no significant differences between Group 1 (BMI<24 kg/m2) and Group 2 (BMI> or =24 kg/m2) in age, basal serum FSH level, estradiol (E2) level and endometrial thickness on hCG day, number of retrieved oocytes and transferred embryos. However, more gonadotropins were used in Group 2 with borderline significance (30.8+/-12.7 ampules vs. 35.4+/-15.3 ampules, p=0.051). The clinical pregnancy rate was significantly lower in Group 2 (25.9% vs. 10.5%, p=0.041) and implantation rate tended to be lower in Group 2 with borderline significance (12.7% vs. 6.8%, p=0.085). CONCLUSION: BMI> or =24 kg/m2 may have a detrimental effect on the IVF-ET outcomes in Korean infertile women, and BMI may be a candidate predictor for IVF outcomes.
