A Case of Pure Red Cell Aplasia.
10.12701/yujm.1988.5.2.239
- Author:
Myung Sook CHOI
;
Chae Hoon LEE
;
Chang Ho CHEON
;
Kyung Dong KIM
;
Chung Sook KIM
;
Myung Soo HYUN
- Publication Type:Case Report
- MeSH:
Anemia;
Anemia, Hemolytic;
Bacteria;
Blood Platelets;
Bone Marrow;
Craniotomy;
Erythrocytes;
Hemoglobinuria;
Humans;
Leukocytes;
Phenytoin;
Red-Cell Aplasia, Pure*;
Reticulocytes
- From:Yeungnam University Journal of Medicine
1988;5(2):239-246
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pure red cell aplasia in uncommon disorder characterized by finding of anemia, absence of nucleated red blood cell in the marrow, absence of reticulocytes in the peripheral blood and normal peripheral platelet and leukocytes counts. We experienced one case of pure red cell aplasia associated with hemolytic anemia characterized by hemoglobinuria, reticulocytopenia, and erythroid hypoplasia of the bone marrow. The cause of the illness was not definitely identified, but we concluded that this patient had simultaneous occurrence of PRCA and hemolytic anemia following administration of diphenylhydantoin after craniotomy rather than virus or bacteria induced. The simultaneous occurrence of PRCA and hemolytic anemia in uncommon and the mechanism for diphenylhydantoin induced PRCA and hemolytic anemia is unclear.