Outcomes of Controlled Ovarian Hyperstimulation/In Vitro Fertilization for Infertile Patients with Borderline Ovarian Tumor after Conservative Treatment.
10.3346/jkms.2007.22.S.S134
- Author:
Chan Woo PARK
1
;
Kwang Moon YANG
;
Hye Ok KIM
;
Sung Ran HONG
;
Tae Jin KIM
;
Kyung Taek LIM
;
Ki Heon LEE
;
Inn Soo KANG
Author Information
1. Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynecology, Cheil General Hospital, Kwandong University College of Medicine, Seoul, Korea. novak21c @yahoo.co.kr
- Publication Type:Original Article
- Keywords:
In Vitro Fertilization;
Borderline Ovarian Tumor;
Conservative Treatment
- MeSH:
Adult;
Embryo Transfer;
Female;
Fertilization in Vitro;
Humans;
Infertility, Female/*complications/*therapy;
Ovarian Neoplasms/*complications/pathology/*surgery;
Ovulation Induction/methods;
Pregnancy;
Pregnancy Complications, Neoplastic;
Prognosis;
Treatment Outcome
- From:Journal of Korean Medical Science
2007;22(Suppl):S134-S138
- CountryRepublic of Korea
- Language:English
-
Abstract:
To evaluate the outcomes of controlled ovarian hyperstimulation (COH)-in vitro fertilization (IVF) such as clinical pregnancy rate (CPR), implantation rate (IR) and live birth rate (LBR) for infertile patients with borderline ovarian tumor (BOT) after conservative treatment, 10 IVF cycles in five patients from January 1999 to July 2005 were analyzed. At the time of diagnosis with BOT, the mean age of patients was 30.0 yr (range, 22-40). For 8 cycles out of 10 attempted IVF cycles, except for 2 cancellation cycles, the mean number of oocytes retrieved was 5.6 (range, 2-16) with a mean fertilization rate of 74.4%. The CPR, IR, and LBR were 50.0% (4/8 cycles), 31.6% (6/19) and 50.0% (4/8 cycles) respectively. The mean follow-up period after COH-IVF initiation was 29.6 (range, 14-61) months. A gynecological oncologist followed all patients every 3 months during the first year and every 6 months thereafter. There was no recurrence during the follow-up period. Our results suggest that COH-IVF may be acceptable for infertile patients with BOT, especially in patients with early-stage BOT after conservative treatment.
