Treatment Outcomes and Quality of Life in Oropharyngeal Cancer after Surgery-based versus Radiation-based Treatment.
- Author:
Tae Wook KIM
1
;
Hye Youn YOUM
;
Hayoung BYUN
;
Young Ik SON
;
Chung Hwan BAEK
Author Information
1. Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. chbaek@skku.edu
- Publication Type:Original Article
- Keywords:
Treatment outcome;
Quality of life;
Oropharyngeal cancer;
Surgery;
Radiation
- MeSH:
Disease-Free Survival;
Humans;
Medical Records;
Oropharyngeal Neoplasms;
Quality of Life;
Survival Rate;
Survivors;
Treatment Outcome;
Surveys and Questionnaires
- From:Clinical and Experimental Otorhinolaryngology
2010;3(3):153-160
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVES: Advances in reconstruction and conservative surgery and the importance of quality of life (QOL) encouraged this reevaluation of surgery-based treatments for oropharyngeal cancer. We tried to compare treatment outcome and QOL after surgery-based versus radiation-based treatment in oropharyngeal cancer. METHODS: The 133 eligible patients were divided into surgery-based and radiotherapy (RT)-based treatment groups. Medical records were reviewed, and EORTC QLQ-C30 and HN65 questionnaires were completed for survivors. Three-year overall survivals, disease-free survivals, locoregional control rates, and QOL scores were compared between the two groups. RESULTS: Demographic data and overall stages were not significantly different between the two groups, and all survival rates were non-significantly different, either. The scores for most QOL items were equivalent, however, for a few items, scores were significantly better in surgery-based group. CONCLUSION: The surgery-based group achieved equivalent treatment outcomes and slightly better QOL scores than the RT-based group. The results of this study suggest that surgery could still be considered as a first-line therapy for oropharyngeal cancer.
