A TSH-secreting pituitary microadenoma diagnosed with inferior petrosal sinus sampling: Case report.
- Author:
Joong Kyung SUNG
1
;
Eun Mi KIM
;
Su Min NAM
;
Young Goo SHIN
;
Choon Hee CHUNG
;
Kum WHANG
;
Jang Hyun KOH
Author Information
1. Department of Internal Mediciney, Yonsei University Wonju College of Medicine, Wonju, Korea.
- Publication Type:Case Report
- Keywords:
alpha-Subunit;
Inferior petrosal sinus sampling;
Pituitary microadenoma;
TSH
- MeSH:
Adenoma;
Adult;
Female;
Humans;
Petrosal Sinus Sampling;
Pituitary Gland;
Pituitary Neoplasms;
Thyrotropin
- From:Korean Journal of Medicine
2009;76(6):752-757
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Thyroid stimulating hormone (TSH)-secreting pituitary adenomas are rare tumors of the pituitary gland and represent 1~2% of all pituitary adenomas. A TSH-secreting pituitary adenoma shows as a normal or elevated thyrotropin level in a hyperthyroid patient. We present a 32-year-old woman who was diagnosed with a TSH-secreting pituitary microadenoma. She had a high free T4, with a normal TSH and alpha-subunit. Bilateral inferior petrosal sinus sampling (IPSS) was done to confirm the alpha-subunit secreting adenoma, and the concentration of the alpha-subunit was high on the tumor side. The pituitary microadenoma was removed, and her TSH and free T4 levels decreased to normal. IPSS may help give an accurate diagnosis in the patient with a normal alpha-subunit.
