A case of severe metabolic acidosis after orthotopic neobladder replacement.
- Author:
Sung Ho HONG
1
;
Dong Hun LEE
;
Byung Moo AHN
;
Sook Eui OH
;
Jin Kyung KIM
;
Young Ki LEE
;
Jung Woo NOH
Author Information
1. Department of Internal Medicine, Hallym Kidney Research Institute, College of Medicine, Hallym University, Seoul, Korea. km2071@unitel.co.kr
- Publication Type:Case Report
- Keywords:
Acidosis;
Urinary bladder;
Bicarbonates
- MeSH:
Acid-Base Equilibrium;
Acidosis;
Bicarbonates;
Colon;
Cystectomy;
Humans;
Hydrogen;
Ileum;
Ions;
Quaternary Ammonium Compounds;
Renal Replacement Therapy;
Research Personnel;
Sodium;
Sodium Bicarbonate;
Ureter;
Urinary Bladder;
Urinary Bladder Neoplasms;
Urinary Diversion
- From:Korean Journal of Medicine
2009;76(6):764-768
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Following a radical cystectomy to treat bladder cancer, the ureters can be implanted in a short loop of ileum, which serves as an orthotopic bladder replacement. However, several investigators have reported the frequent development of a normal anion gap metabolic acidosis and electrolyte disturbance in these patients. The colon segments secrete sodium and bicarbonate ions and reabsorb ammonium, hydrogen, and chloride ions when exposed to urine, causing metabolic acidosis. In most cases, the acid-base disorder is not very troublesome. The metabolic acidosis can usually be corrected by administering sodium bicarbonate. We experienced a case of severe metabolic acidosis associated with urinary diversion that improved with continuous renal replacement therapy (CRRT).
