Twin pregnancy with diploid partial hydatidiform mole and coexisting fetuses following in vitro fertilization and embryo transfer: A case report.
10.5468/kjog.2010.53.5.443
- Author:
Eun Kyoung KIM
1
;
Young Ju JEONG
Author Information
1. Department of Obstetrics and Gynecology, Chonbuk National University Medical School, Jeonju, Korea. yjjeong@jbnu.ac.kr
- Publication Type:In Vitro ; Case Report
- Keywords:
Diploid;
In vitro fertilization and embryo transfer;
Partial hydatidiform mole;
Twin pregnancy;
Ultrasonography
- MeSH:
Amniocentesis;
Diploidy;
Embryo Transfer;
Embryonic Structures;
Female;
Fertilization in Vitro;
Fetus;
Follow-Up Studies;
Gestational Age;
Gestational Trophoblastic Disease;
Humans;
Hydatidiform Mole;
Karyotype;
Molar;
Placenta;
Pregnancy;
Pregnancy, Twin;
Uterine Contraction;
Young Adult
- From:Korean Journal of Obstetrics and Gynecology
2010;53(5):443-448
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 24-year-old woman, gravida 1, para 0, was referred to our hospital at 14 weeks of gestation due to suspected twin pregnancy with hydatidiform mole and coexisting fetuses. The present pregnancy was achieved following in vitro fertilization and embryo transfer (IVF-ET). Ultrasound examinations at 14 weeks 3 days of gestation revealed a live fetus appropriate for assigned gestational age with a normal-looking placenta and a dead fetus with an additional echogenic mass resembling molar placenta. The patient was planned to take amniocentesis for chromosomal analysis. However, regular uterine contraction was developed and spontaneous expulsion was occurred at 14 weeks 4 days of gestation. Chromosomal analysis of twin pregnancy using normal and molar placental tissues revealed normal karyotype with 46,XY, 46,XX, respectively. Follow-up showed no progression to persistent gestational trophoblastic disease. We present a twin pregnancy with diploid partial hydatidiform mole and coexisting fetuses that occurred following IVF-ET, which was aborted spontaneously.
