Delayed Flumazenil Injection after Endoscopic Sedation Increases Patient Satisfaction Compared with Immediate Flumazenil Injection.
- Author:
Hyun Jung CHUNG
1
;
Byoung Wook BANG
;
Hyung Gil KIM
;
Kye Sook KWON
;
Yong Woon SHIN
;
Seok JEONG
;
Don Haeng LEE
;
Shin Goo PARK
Author Information
1. Division of Gastroenterology, Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea. bangbu@inha.ac.kr
- Publication Type:Original Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
- Keywords:
Colonoscopy;
Flumazenil;
Midazolam;
Patient satisfaction
- MeSH:
Adult;
Anesthesia Recovery Period;
Endoscopy/adverse effects;
Female;
Flumazenil/*administration & dosage;
GABA Modulators/*administration & dosage;
Humans;
Male;
Memory/drug effects;
Middle Aged;
Pain/epidemiology;
*Patient Satisfaction;
Prospective Studies;
Time Factors;
Treatment Outcome
- From:Gut and Liver
2014;8(1):7-12
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: Flumazenil was administered after the completion of endoscopy under sedation to reduce recovery time and increase patient safety. We evaluated patient satisfaction after endoscopy under sedation according to the timing of a postprocedural flumazenil injection. METHODS: In total, 200 subjects undergoing concurrent colonoscopy and upper endoscopy while sedated with midazolam and meperidine were enrolled in our investigation. We randomly administered 0.3 mg of flumazenil either immediately or 15 minutes after the endoscopic procedure. A postprocedural questionnaire and next day telephone interview were conducted to assess patient satisfaction. RESULTS: Flumazenil injection timing did not affect the time spent in the recovery room when comparing the two groups of patients. However, the subjects in the 15 minutes injection group were more satisfied with undergoing endoscopy under sedation than the patients in the immediate injection group according to the postprocedural survey (p=0.019). However, no difference in overall satisfaction, memory, or willingness to undergo a future endoscopy was observed between the two groups when the telephone survey was conducted on the following day. CONCLUSIONS: This study demonstrated that a delayed flumazenil injection after endoscopic sedation increased patient satisfaction without prolonging recovery time, even though the benefit of the delayed flumazenil injection did not persist into the following day.
