A Case of Relapsing Polychondritis Improved by Infliximab Treatment.
10.4078/jrd.2014.21.3.166
- Author:
Sang Jin LEE
1
;
Ji Ae YANG
;
Jun Won PARK
;
Dong Jin KO
;
Hyun Mi KWON
;
Jin Young MOON
;
Young Ki KIM
;
Young Hoon CHOI
;
Eun Young LEE
Author Information
1. Department Internal Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea. elee@snu.ac.kr
- Publication Type:Case Report
- Keywords:
Relapsing polychondritis;
Infliximab
- MeSH:
Biological Factors;
Cartilage;
Ear;
Heart Valves;
Immunosuppressive Agents;
Inflammation;
Joints;
Korea;
Nose;
Polychondritis, Relapsing*;
Respiratory System;
Skin;
Infliximab;
Rituximab
- From:Journal of Rheumatic Diseases
2014;21(3):166-169
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Relapsing polychondritis is an episodic, systemic inflammation of the cartilage with unknown autoimmune etiology. It leads to the destruction of cartilaginous structures of the ear, eye, nose, respiratory tract, joints, skin, and heart valve, and its presented symptoms are diverse. It can be improved mainly by corticosteroid or immunosuppressive agents. Recently, the use of biologic agents (TNF inhibitors, rituximab, tocilizumab et al) was reported from abroad. However, there is no reported case of relapsing polychondritis, which is treated by biologic agents in Korea. We report this first case of refractory relapsing polychondritis, which was improved with a treatment of Infliximab.