Molecular Targeted Therapy in Modern Oncology: Imaging Assessment of Treatment Response and Toxicities.
- Author:
Katherine M KRAJEWSKI
1
;
Marta BRASCHI-AMIRFARZAN
;
Pamela J DIPIRO
;
Jyothi P JAGANNATHAN
;
Atul B SHINAGARE
Author Information
- Publication Type:Review
- Keywords: Vascular endothelial growth factor; Response Evaluation Criteria in Solid Tumors; Epidermal growth factor receptor; Anaplastic lymphoma kinase; Mammalian target of rapamycin; Human epidermal growth factor receptor 2
- MeSH: Drug-Related Side Effects and Adverse Reactions; Humans; Molecular Targeted Therapy*; Receptor, Epidermal Growth Factor; Response Evaluation Criteria in Solid Tumors; Tumor Microenvironment; Vascular Endothelial Growth Factor A
- From:Korean Journal of Radiology 2017;18(1):28-41
- CountryRepublic of Korea
- Language:English
- Abstract: Oncology is a rapidly evolving field with a shift toward personalized cancer treatment. The use of therapies targeted to the molecular features of individual tumors and the tumor microenvironment has become much more common. In this review, anti-angiogenic and other molecular targeted therapies are discussed, with a focus on typical and atypical response patterns and imaging manifestations of drug toxicities.