Management and prevention of delayed gastric emptying after pancreaticoduodenectomy.
10.14701/kjhbps.2012.16.1.1
- Author:
Yong Hoon KIM
1
Author Information
1. Division of Hepato-Biliary-Pancreatic Surgery, Department of Surgery, Keimyung University School of Medicine, Daegu, Korea. hbps@dsmc.or.kr
- Publication Type:Review
- Keywords:
Pancreaticoduodenectomy;
Delayed gastric emptying;
Therapy;
Prevention
- MeSH:
Ataxia;
Autonomic Nervous System;
Diagnosis, Differential;
Fees and Charges;
Gastric Emptying;
Incidence;
Ischemia;
Myocytes, Smooth Muscle;
Neurons;
Pancreaticoduodenectomy;
Quality of Life
- From:Korean Journal of Hepato-Biliary-Pancreatic Surgery
2012;16(1):1-6
- CountryRepublic of Korea
- Language:English
-
Abstract:
Although technical advances have been made in pancreaticoduodenectomy, the incidence of delayed gastric emptying (DGE) is reported as being high. Postoperative DGE is not fatal, but often results in prolonging the length of patients' stay in hospital, increasing their medical expenses, and further lowering their quality of life. DGE is a complex process caused by disorder and incoordination of various factors in charge of gastric mobility, such as smooth muscle cells (myogenic), enteric neuron (hormonal), and autonomic nervous system (neural). DGE often occurs after operative maneuvers that cause the loss of organs responsible for gastric motility and emptying or kinetic muscular or neuromuscular ischemia. To prevent DGE, it is most important to develop and universalize a standardized surgical technique in a way to reduce factors that are considered to cause DGE after pancreaticoduodenectomy. Moreover, if it is suspected that DGE occurred after pancreaticoduodenectomy, a differential diagnosis from diseases with similar symptoms via an accurate diagnostic approach should be implemented.
