Extended Spectrum beta-lactamase-producing E. coli-related Nosocomial Peritonitis Treated Successfully with Meropenem in a Patient on Peritoneal Dialysis.
- Author:
Seong Kyu JEONG
1
;
Yeong Hee HAM
;
Jin Hyuk JO
;
Yeong Sin SIN
;
Dong HEO
;
Hark RIM
Author Information
- Publication Type:Case Report
- Keywords: Escherichia coli; Extended spectrum beta-lactamase; Peritoneal dialysis; Peritonitis
- MeSH: Anti-Bacterial Agents; Catheters; Dialysis; Escherichia coli; Humans; Imipenem; Peritoneal Dialysis; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Recurrence; Staphylococcus aureus; Staphylococcus epidermidis; Thienamycins; Ultrafiltration
- From:Kosin Medical Journal 2013;28(1):43-47
- CountryRepublic of Korea
- Language:Korean
- Abstract: Peritonitis is a common and potentially serious infection in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). The most common organisms usually associated with CAPD peritonitis are Staphylococcus aureus and Staphylococcus epidermidis. Rarely, aerobic gram negative bacilli have been the causative agents of CAPD peritonitis. The treatment of CAPD peritonitis requires removal of the peritoneal catheter and treatment with parenteral antibiotics active against the causative pathogen. While hospitalized for CAPD peritonitis, a 55-year-old man on CAPD had nosocomial peritonitis secondary to infection by ESBL-producing E.coli, that was sensitive to imipenem and meropenem. He was treated successfully with a 4-week course of intraperitoneal meropenem therapy without subsequent relapse, loss of peritoneal catheter, ultrafiltration failure, or dialysis inadequacy.
