A Case of Nodular Regenerative Hyperplasia of the Liver Combined with Toxic Hepatitis.
- Author:
Sun Mi JIN
1
;
Sang Hee SONG
;
Yang Hyun CHO
;
Dae Kyu SHIN
;
Sun Young SHIN
;
Gwang Il KIM
;
Hana PARK
;
Kyu Sung RIM
Author Information
- Publication Type:Case Reports
- Keywords: Nodular regenerative hyperplasia; Drug-induced liver injury; Liver diseases
- MeSH: Alanine Transaminase/analysis; Aspartate Aminotransferases/analysis; Bilirubin/blood; Chemical and Drug Induced Liver Injury/complications/*diagnosis/pathology; Duodenal Ulcer/pathology; Endoscopy, Digestive System; Female; Focal Nodular Hyperplasia/complications/*diagnosis/pathology; Humans; Liver/enzymology/pathology; Magnetic Resonance Imaging; Middle Aged; Tomography, X-Ray Computed
- From:The Korean Journal of Gastroenterology 2015;65(1):52-56
- CountryRepublic of Korea
- Language:English
- Abstract: Nodular regenerative hyperplasia (NRH) is an uncommon liver condition characterized by diffuse transformation of the hepatic parenchyma into regenerative nodules without fibrosis. Portal vasculopathy caused by abnormal hepatic venous flow may induce hepatocyte hyperplasia, which forms regenerative nodules. Underlying diseases or certain drugs may also be the cause of NRH. This condition is often underdiagnosed as the patients remain asymptomatic until development of portal hypertension, and histopathologic confirmation by liver biopsy is the only way of making a definite diagnosis. The management mainly involves prevention and treatment of the complications of portal hypertension. The frequency of diagnosis of NRH has increased rapidly in recent years, however, only a few cases have been reported in Korea. Here, we report on a case of NRH of the liver combined with toxic hepatitis.
