Clinical Experience with Lederkyn in Genito-urinary Diseases.
- Author:
Key Ha PARK
1
;
Hak Lim KIM
;
Hak Song LEE
Author Information
1. Department of Urology, Seoul National University, College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
chronic prostatitis;
cystitis;
urethritis;
Lederky
- MeSH:
Administration, Oral;
Bacterial Infections;
Body Fluids;
Cystitis;
Diffusion;
Gastrointestinal Tract;
Kidney;
Plasma;
Prostatitis;
Urethritis
- From:Korean Journal of Urology
1960;1(1):65-67
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lerderkyn, a recently introduced sulfonamide, has been administrated to 11 cases in doses ranging from 1 to 3 gm daily. The compound is rapidly absorbed from the gastrointestinal tract and therapeutically effective plasma concentration is maintained rapidly and for many hours, following the oral administration. The diffusion of Ledrkyn into the tissue and the body fluid occurs readily and is slowly excreted through the kidney. Maintenance of effective concentration in urine for many hours results in successful treatment especially for genito-urinary tract infection. In this study, five acute gonococcal urethritis, one non-gonococcal urethritis, two acute cystitis, three chronic prostatitis have been treated with this drug in doses of 1 to 3 gm daily and very satisfactory results obtained in acute bacterial infection.
