A Case of Acute Monoblastic Leukemia developed during Pregnancy.
- Author:
Seong Hee KIM
1
;
Keon Ho PARK
;
Jin Sil PARK
;
Hyun Hee KIM
;
Sung Ro CHUNG
;
Hyung MOON
;
Moon Il PARK
Author Information
1. Department of Obstetrics and Gynecology, School of Medicine, Hanyang University, Seoul, Korea. parkmi@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Acute leukemia;
Second trimester;
Combination chemotherapy
- MeSH:
Adult;
Drug Therapy, Combination;
Early Diagnosis;
Female;
Fetus;
Humans;
Incidence;
Leukemia;
Leukemia, Monocytic, Acute*;
Metrorrhagia;
Pregnancy Trimester, Second;
Pregnancy*;
Prognosis;
Uterus
- From:Korean Journal of Perinatology
2003;14(2):201-206
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Acute leukemias are among the most common malignant neoplasms of young woman, but paradoxically, their incidence complicating pregnancy is cited to be very low. In most situations, the course of the pregnancy does not seem to be affected by the presence of the leukemia. So early diagnosis and treatment of acute leukemia might be very important., since acute leukemia in a pregnant young woman poses an immediate threat to life and any treatment delay would significantly worsen the patient's prognosis. We report a 37-year-old female who had symptoms and signs of acute leukemia such as vaginal spotting and leukemia cutis and was diagnosed as acute monoblastic leukemia M5(FAB) in January 2002 with 25 weeks' pregnancy. This case represents the use of combination chemotherapy successfully resulted in complete remission in the second trimester without any adverse impact on the fetus in uterus.
