A Case of Methotrexate Induced Liver Cirrhosis.
- Author:
Gwang Gook KIM
;
Seok Ho DONG
;
Hyo Jeong LEE
;
Hyo Jong KIM
;
Byung Ho KIM
;
Young Woon CHANG
;
Jung Il LEE
;
Rin CHANG
- Publication Type:Case Report
- Keywords:
Methotrexate;
Psoriasis;
Liver cirrhosis
- MeSH:
Bone Marrow;
Humans;
Liver Cirrhosis*;
Liver*;
Lung Diseases, Interstitial;
Methotrexate*;
Psoriasis
- From:Korean Journal of Medicine
1997;53(3):431-435
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Methotrexate has been used to treat refractory psoriasis for many years. Despite its well-established clinical efficacy, drawbacks to methotrexate usage include a number of deleterious effects including hepatotoxicity, bone marrow suppression, and interstitial pneumonitis. We experienced a case of liver cirrhosis m patient with active psoriasis receiving long-term ora1 methotrexate therapy, and reported this case with review of literature.