The Results of Antimalarial Treatment of Resurgent Vivax Malaria in Korea.
- Author:
Chae Seung LIM
1
;
Kyung Ran MA
;
Young Kee KIM
;
Kap No LEE
;
Kwang Hee KIM
;
Min Ja KIM
;
Won Kyu KHO
;
Dae Sung KIM
Author Information
1. Departments of Clinical Pathology, College of Medicine, Korea University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Plasmodium vivax;
Korea;
Treatment;
Chloroquine;
Primaquine
- MeSH:
Azure Stains;
Chloroquine;
Diagnosis;
Gyeonggi-do;
Humans;
Incidence;
Korea*;
Malaria;
Malaria, Vivax*;
Military Personnel;
Parasitemia;
Plasmodium vivax;
Primaquine;
Recurrence
- From:Korean Journal of Infectious Diseases
1997;29(5):413-416
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: We evaluated the posttreatment response to chloroquine among 81 patients with vivax malaria who were residents in Northern area of Kyunggi province in 1996. The result of chloroquine therapy was followed 28 days after treatment. Material and METHODS: Diagnosis of malaria was made by microscopic examination of Giemsa stain of peripheral blood. Parasitemia levels from each patient were counted before treatment, 3, 14 and 28 days after treatment. RESULTS: Eight-one patients successfully completed the therapy. All patients were army soldiers, who were residing in northern area of Kyunggi province. The 14-day cumulative incidence of therapeutic failure for P. vivax was 2.5% (n=2) and 0% (n=81) at 28th day. One patient had a recurrence eight months after completion of antimalarial treatment. CONCLUSION: The results suggest that recent resurgent malaria in Korea need more careful therapy. Antimalarial treatment should not be completed without microscopic confirmation.
