Langerhans Cell Sarcoma in Two Young Children: Imaging Findings on Initial Presentation and Recurrence.
10.3348/kjr.2013.14.3.520
- Author:
Woong Do CHUNG
1
;
Soo Ah IM
;
Nak Gyun CHUNG
;
Gyeong Sin PARK
Author Information
1. Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul 137-701, Korea. saim@catholic.ac.kr
- Publication Type:Case Reports
- Keywords:
Langerhans cell sarcoma;
Langerhans cell histiocytosis;
CT;
MR
- MeSH:
Female;
Hepatomegaly/diagnosis;
Humans;
Infant;
Langerhans Cell Sarcoma/*diagnosis;
Magnetic Resonance Imaging;
Mediastinal Neoplasms/*diagnosis;
Neoplasm Recurrence, Local;
Skull Neoplasms/*diagnosis;
Splenomegaly/diagnosis;
Tomography, X-Ray Computed
- From:Korean Journal of Radiology
2013;14(3):520-524
- CountryRepublic of Korea
- Language:English
-
Abstract:
Langerhans cell sarcoma (LCS) is a neoplastic proliferation of Langerhans cells with malignant cytological features and multi-organ involvement that typically has a poor prognosis. We experienced 2 cases of LCS in children less than 2 years of age and report them based primarily on CT and MR findings. Both children had findings of hepatosplenomegaly with low-attenuation nodular lesions, had multiple lymphadenopathy, and had shown recurrent lesions invading the skull during follow-up after chemotherapy.
