Histiocytic Medullary Reticulosis in childhood Report of Three Cases.
- Author:
Kwan Sub CHUNG
1
;
Kyo Sun KIM
;
Do Kwang YUN
;
Pyung Kil KIM
;
Kir Young KIM
;
Byung Soo KIM
;
Tae Jung KWON
;
In Jun CHOR
Author Information
1. Deptartment of Pediatirics and Yonsei University, Seoul, Korea.
- Publication Type:Original Article
- MeSH:
Agranulocytosis;
Anemia;
Bone Marrow;
Child;
Diagnosis;
Drug Therapy;
Histiocytes;
Humans;
Lymph Nodes;
Prednisolone;
Thrombocytopenia;
Vinblastine
- From:Journal of the Korean Pediatric Society
1980;23(10):833-842
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Three cases of hisiocytic medullary reticulosis occurring in children aged 6 years, 9 years and 14 years, are described. In all children the diagnosis was based on anemia, granulocytopenia, thrombocytopenia and marked erythrophagocytosis by bone marrow and lymph node atypical histiocytes. They all showed immediate remission with combined chemotherapy of vinblastine and prednisolone, but Case 1 eventually died at 6 months after onset of this rapidly progressive, fatal illness and Case 2, 3 are alive 14 months after onset of their illness.
