A Case of Malignancy-associated Histiocytoid Sweet Syndrome in a Patient with AML.
- Author:
Jeong Wan SEO
1
;
Tae Hoon KIM
;
Seung Hwan CHOI
;
Seung Min HA
;
Ki Hoon SONG
;
Ki Ho KIM
Author Information
1. Department of Dermatology, College of Medicine, Dong-A University, Busan, Korea. khkim@dau.ac.kr
- Publication Type:Case Report
- Keywords:
Malignancy-associated Sweet syndrome;
Histiocytoid Sweet syndrome;
AML
- MeSH:
Biopsy;
Fever;
Hand;
Histiocytes;
Humans;
Leukemia, Myeloid, Acute;
Leukocytosis;
Middle Aged;
Myeloid Cells;
Recurrence;
Sweet Syndrome*
- From:Korean Journal of Dermatology
2017;55(2):124-128
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sweet syndrome is a disorder characterized by painful, erythematous, cutaneous plaques and nodules of rapid onset accompanied by fever, leukocytosis, and neutrophilia. We encountered a case of a recurrent histiocytoid Sweet syndrome in a patient with acute myeloid leukemia (AML). A 64-year-old Korean man was diagnosed with complete remission of AML and had symptomatic nodules and plaques on the dorsal sides of both hands. Approximately 3 years prior, he also had symptomatic plaques at the same site and had been diagnosed with MDS (Myelodysplastic syndrome). We performed a biopsy and diagnosed this case as a malignancy-associated histiocytoid Sweet syndrome. Most Sweet syndrome cases are acute; in contrast, this case was chronic with a relapse. In addition, histopathologic examination showed a dense histiocytic infiltration. These histiocytoid cells are usually misinterpreted as histiocytes; however, they are actually immature myeloid cells. Herein, we report a case of a recurrent malignancy-associated histiocytoid Sweet syndrome in a patient with a hematologic disorder.
