Effects of sodium hyaluronate on filtration bleb in rabbits.

Author: Sung Min HYUNG ¹ ; Dong Myung KIM ; Chul HONG ; Dong Ho YOUN
Author Information

1. Department of Ophthalmology, College of Medicine, Chungbuk National University, Cheongju, Chungbuk, Korea.
Publication Type:Original Article ; Research Support, Non-U.S. Gov't
Keywords: filtration bleb; hypotony; Sodium hyaluronate; posterior-lip sclerectomy; rabbits
MeSH: Animals; Anterior Chamber/*drug effects/pathology; Conjunctiva/pathology; Connective Tissue/pathology; Follow-Up Studies; Hyaluronic Acid/*administration & dosage; Ocular Hypotension/prevention & control; Rabbits; Sclera/pathology; *Sclerostomy
From:Korean Journal of Ophthalmology 1993;7(1):11-15
CountryRepublic of Korea
Language:English
Abstract: Sodium hyaluronate can be used during a trabeculectomy to prevent early postoperative hypotony and shallow anterior chamber. To determine its long-term effect on the outcome of filtration surgery, fifteen rabbits underwent a osterior-lip sclerectomy in both eyes. Into their right eyes 0.2ml sodium hyaluronate, and into left eyes 0.2ml balanced salt solution were injected intracamerally. Gross and histopathological differences of bleb were observed. There was no statistically significant difference in longevity of the filtration bleb.