A Case of Metastatic Angiosarcoma Diagnosed by Liquid-Based Preparation: Peculiar Cytoplasmic Changes.
- Author:
Min Jung JUNG
1
;
Young Ok KIM
Author Information
1. Department of Pathology, Kosin University College of Medicine, Busan, Korea. suajoon@kosinmed.or.kr
- Publication Type:Case Report
- Keywords:
Hemangiosarcoma;
Cytodiagnosis;
Cytologic techniques;
Diagnosis;
Differential;
Liquid based preparation
- MeSH:
Cytodiagnosis;
Cytoplasm*;
Diagnosis;
Hemangiosarcoma*;
Immunochemistry;
Soft Tissue Neoplasms;
Vacuoles
- From:Korean Journal of Pathology
2014;48(3):241-247
- CountryRepublic of Korea
- Language:English
-
Abstract:
Angiosarcoma with predominantly epithelioid features is a rare soft tissue neoplasm and the interpretation of its cytopathologic findings may be difficult. We report a case of metastatic angiosarcoma with predominantly epithelioid features diagnosed by liquid-based cytology. The cytopathologic findings in this case differed from those of the conventional preparation and we found a clean background, no hyperchromatic nuclei and several cytoplasmic changes, including intracytoplasmic vacuoles with peculiar shapes, juxtanuclear condensation and perinuclear clearing. Identification of these changes using liquid-based cytology supplemented with immunochemistry may be helpful in reaching a correct cytopathologic diagnosis.
